The Vinculin antibody from Wuhan Fine Biotech Co., Ltd. is a Mouse Monoclonal antibody to VCL, and Vinculin. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Vinculin antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament(F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin(124 kDa), is muscle-specific